Ankylosing Spondylitis

 Ankylosing spondylitis (AS) is a chronic autoimmune disorder that affects the spine and sacroiliac joints. It is characterized by inflammation of the joints between the vertebrae of the spine and the joints between the spine and the pelvis. The exact cause of AS is unknown, but it is believed to be a combination of genetic and environmental factors. In this article, we will discuss the causes, symptoms, and treatments for AS, as well as ways to manage the condition.

Causes of Ankylosing Spondylitis

The exact cause of AS is unknown, but it is believed to be a combination of genetic and environmental factors. The condition is associated with a genetic marker called HLA-B27, which is present in about 90% of people with AS. However, not everyone with this marker develops the condition. Environmental factors, such as infections or injuries, may also play a role in the development of AS.

Symptoms of Ankylosing Spondylitis

Symptoms of AS can vary depending on the severity of the condition. The most common symptoms include back pain and stiffness, particularly in the lower back and hips. Other symptoms may include fatigue, loss of appetite, and weight loss. In some cases, the condition can also affect other joints, such as the shoulders, hips, and knees.

Eye symptoms can also occur in AS, and may include iritis, uveitis, and conjunctivitis, which are inflammation of the iris, uvea, and conjunctiva respectively.

Diagnosis and Treatment

Diagnosis of AS is typically made through a combination of a physical examination, laboratory tests, such as blood tests and imaging studies, and a review of the patient's medical history. It's important to note that the symptoms of AS are similar to those of other conditions, such as osteoarthritis or other forms

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