Corneal Stem Cell Transplant: Understanding and Managing a Revolutionary Treatment for Corneal Damage

Introduction 

Corneal stem cell transplant, also known as limbal stem cell transplant, is a revolutionary treatment for corneal damage that has the potential to restore vision and improve the appearance of the eye. This procedure is typically performed to replace damaged or diseased stem cells in the cornea with healthy ones, allowing the eye to regenerate and heal. In this article, we will discuss the causes, symptoms, and management of corneal stem cell transplant.

Causes 

Corneal stem cell transplant may be recommended in cases of:

  • Corneal stem cell deficiency: Stem cell deficiency can be caused by a variety of conditions, including chemical burns, Stevens-Johnson syndrome, and limbal stem cell deficiency, and can lead to corneal opacification and blindness.
  • Corneal injury: Injury to the cornea can damage or destroy the stem cells in the limbus, leading to corneal opacification and blindness.
  • Corneal disease: Certain diseases, such as ocular surface squamous neoplasia, can cause damage to the limbal stem cells, leading to corneal opacification and blindness.

Symptoms 

Symptoms of corneal stem cell deficiency can include:

  • Blurred vision
  • Distorted vision
  • Sensitivity to light
  • Glare and halos around lights
  • Redness or irritation of the eye
  • The feeling of a "gritty" sensation in the eye
  • Episodes of severe eye pain
  • Cloudy or opaque vision
  • Decreased visual acuity
  • A white ring around the iris
  • Sticky or gritty eyes

Diagnosis 

Corneal stem cell transplant is typically recommended based on a thorough eye examination, diagnostic tests such as a corneal topography, pachymetry, and a slit-lamp examination. Your doctor may also do a visual acuity test to measure your visual acuity and a Schirmer's test to measure the amount of tears produced.

Procedure 

Corneal stem cell transplant is typically performed as an outpatient procedure, meaning that the patient does not have to stay overnight in the hospital. The procedure is usually done under general anesthesia and takes about 2-4 hours.

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